A proteomic and genomic investigation into the role of lamin A in colorectal cancer cell motility

Lamins are type V intermediate filament proteins found at the nuclear envelope. Expression of lamin A in colorectal cancer (CRC) tumours is correlated with poor prognosis and expression of lamin A in CRC cell lines promotes greatly increased cell motility. The aim of this study was to identify prote...

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Bibliographic Details
Main Author: Foster, Clare Ruth
Published: Durham University 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.548138