Regulation of lymphocyte trafficking to the human gut in physiology and disease

Memory T cell recruitment to the non-lymphoid tissue of the intestine (the gut lamina propria) requires the interactions between integrin a4B7 and its ligand Mucosal Addressin Cell Adhesion Molecule-1 (MAdCAM-1), which is exclusively expressed in the gut microvasculature. T cell homing to small inte...

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Bibliographic Details
Main Author: Wang, Amu
Other Authors: Marelli-Berg, Federica ; Orchard, Timothy
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544302