A PDK1-dependent regulation of PLCγ1 activation is essential for cancer cell migration and invasion
Phospholipase Cγ1 (PLCγ1) is highly expressed in several tumours such as breast carcinomas and has been found overexpressed in metastases compared to primary tumour in breast cancer patients, indicating that PLCγ1 may be important in tumourigenesis and metastasis dissemination. PLCγ1 involvement in...
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Queen Mary, University of London
2011
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538752 |