Altered expression of ion channels in hyperinsulinism
The ability of the pancreatic β-cell to secrete insulin in response to changes in glucose concentration is the cornerstone of glucose homeostasis. The β-cell couples glucose metabolism to electrical activity via the modulation of ion channel activity. Defects in β-cell ion channels can result in the...
Main Author: | Adams, Leon |
---|---|
Other Authors: | Dunne, Mark |
Published: |
University of Manchester
2011
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538515 |
Similar Items
-
Genotype/phenotype relationships in diabetes & hyperinsulinism resulting from KATP channel mutations
by: Flanagan, S. E.
Published: (2007) -
Congenital hyperinsulinism : a unique model to study pancreatic islet cell development and maintenance
by: Shi, Yanqin
Published: (2014) -
Type II diabetes and the pancreatic B cell : molecular characterisation of ion channel and transporter polymorphisms
by: Nicolson, Tamara Jane
Published: (2010) -
Divalent metal ions and the pancreatic B-cell : role in the pathogenesis of type 2 diabetes
by: Bellomo, Elisa
Published: (2010) -
Patterns of heparan sulfate and FGF ligand expression in pancreatic islets and roles in paracrine regulation
by: Theodoraki, A.
Published: (2014)