Regulation of dual specificity phosphatase 1 gene expression by glucocorticoids

Regulation of dual specificity phosphatase 1 gene expression by glucocorticoids

Dual specificity phosphatase 1 (DUSP1) limits the expression of pro-inflammatory gene products by dephosphorylating and inactivating mitogen-activated protein kinases (MAPKs), in particular p38 MAPK and cJun N-terminal kinase. In many mouse and human cell types, glucocorticoids (GCs) increase the ex...

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Bibliographic Details
Main Author:	Silva Martins, Joana Rita
Other Authors:	Clark, Andy
Published:	Imperial College London 2010
Subjects:	615.1
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518971

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