Genetic variation underlying anxiety-like behaviour in laboratory mouse strains

Genetic variation underlying anxiety-like behaviour in laboratory mouse strains

Strain differences have previously been observed in the anxiolytic effect of the Angiotensin Type I receptor (AT1 R) antagonist losartan in mice. Structural variation in key binding sites, AT1 receptor binding, AT1 expression, the effect of a microsatellite in the promoter region of the gene and the...

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Main Author: Golding, Bruno J. D.
Published: University of Brighton 2009
Subjects:
615.1
B000 Health Professions
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518245
id ndltd-bl.uk-oai-ethos.bl.uk-518245
record_format oai_dc
spelling ndltd-bl.uk-oai-ethos.bl.uk-5182452018-10-16T03:23:50ZGenetic variation underlying anxiety-like behaviour in laboratory mouse strainsGolding, Bruno J. D.2009Strain differences have previously been observed in the anxiolytic effect of the Angiotensin Type I receptor (AT1 R) antagonist losartan in mice. Structural variation in key binding sites, AT1 receptor binding, AT1 expression, the effect of a microsatellite in the promoter region of the gene and the influence of angiotensin receptor associated protein (ATRAP) were investigated for association with this observed behavioural variation.615.1B000 Health ProfessionsUniversity of Brightonhttps://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518245https://research.brighton.ac.uk/en/studentTheses/72990e34-ef32-490c-a724-4ef9a66f67f9Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 615.1
B000 Health Professions
spellingShingle 615.1
B000 Health Professions
Golding, Bruno J. D.
Genetic variation underlying anxiety-like behaviour in laboratory mouse strains
description Strain differences have previously been observed in the anxiolytic effect of the Angiotensin Type I receptor (AT1 R) antagonist losartan in mice. Structural variation in key binding sites, AT1 receptor binding, AT1 expression, the effect of a microsatellite in the promoter region of the gene and the influence of angiotensin receptor associated protein (ATRAP) were investigated for association with this observed behavioural variation.
author Golding, Bruno J. D.
author_facet Golding, Bruno J. D.
author_sort Golding, Bruno J. D.
title Genetic variation underlying anxiety-like behaviour in laboratory mouse strains
title_short Genetic variation underlying anxiety-like behaviour in laboratory mouse strains
title_full Genetic variation underlying anxiety-like behaviour in laboratory mouse strains
title_fullStr Genetic variation underlying anxiety-like behaviour in laboratory mouse strains
title_full_unstemmed Genetic variation underlying anxiety-like behaviour in laboratory mouse strains
title_sort genetic variation underlying anxiety-like behaviour in laboratory mouse strains
publisher University of Brighton
publishDate 2009
url https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518245
work_keys_str_mv AT goldingbrunojd geneticvariationunderlyinganxietylikebehaviourinlaboratorymousestrains
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