Development of a three-dimensional, all-human in vitro model of the blood-brain barrier for cancer metastasis studies

Background: Around 20-40% of cancers will spread to the brain by passing through the physical blood-brain barrier and thereby worsen prognosis. Unfortunately, there is not a reliable model that closely mimics the in vivo situation which can be used in cancer cell invasion studies. In vitro models of...

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Bibliographic Details
Main Author: Fry, Kathryn Emily
Published: University of Portsmouth 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511399