The role of protein degradation in neuronal cell death
In neuronal systems, the degradation of intracellular proteins, controlled by the ubiquitin-proteasome system and autophagy, is of paramount importance for normal cellular homeostasis. The dysfunction of either of these pathways leads to the accumulation of protein aggregates, as seen in neurodegene...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
University of Leicester
2009
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510474 |