Mechanisms for establishing transcriptional competence of tissue-specific genes in pluripotent stem cells
Tissue-specific genes have been found to be epigenetically marked in embryonic stem cells by different combination of histone modifications. These marks are believed to prime genes for activation at later stages of development. Previous work has revealed the presence of one such signature on one enh...
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Imperial College London
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506479 |