An investigation of the behaviour of superoxide dismutase 1 in in-vitro models of motor neuron disease

Motor neuron disease is an incurable neurodegenerative condition. A proportion of motor neuron disease is inherited in autosomal dominant manner, of which approximately 10% is due to mutations in the enzyme superoxide dismutase 1 (SOD1). The mechanism by which mutant SOD1 selectively kills motor neu...

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Bibliographic Details
Main Author: Stevens, James Clement
Published: University College London (University of London) 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505240

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