Modulation of the Co-Chaperone AHA1 Affects HSP90 Function in Cancer Cells

Modulation of the Co-Chaperone AHA1 Affects HSP90 Function in Cancer Cells

AHAl (Activator ofHSP90 ATPase) is a co-chaperone of the ATP-dependent molecular chaperone Heat shock protein 90 (HSP90) which is involved in the maturation, stabilization/degradation and function of oncogenic proteins. HSP90 operates in a multimeric complex driven by the binding and hydrolysis of A...

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Bibliographic Details
Main Author:	Holmes, Joanna Louise
Published:	Institute of Cancer Research (University Of London) 2008
Subjects:	616.994
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.504791

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