Metal-based approaches to C(1)-substituted glycals

A new metal-based method to synthesize C(1)-substituted glycals has been developed. Starting with the obtained substituted C-glycals, the possibility of a stereocontrolled addition (via azidoselenation) to form β-C-substituted-2-aminoglycosides has been investigated. Instead of forming the expected...

Full description

Bibliographic Details
Main Author:	Wang, Junwei
Published:	University of Bristol 2009
Subjects:	547.78
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503863

id	ndltd-bl.uk-oai-ethos.bl.uk-503863
record_format	oai_dc
spelling	ndltd-bl.uk-oai-ethos.bl.uk-5038632015-03-20T05:43:46ZMetal-based approaches to C(1)-substituted glycalsWang, Junwei2009A new metal-based method to synthesize C(1)-substituted glycals has been developed. Starting with the obtained substituted C-glycals, the possibility of a stereocontrolled addition (via azidoselenation) to form β-C-substituted-2-aminoglycosides has been investigated. Instead of forming the expected C-glycosyl derivatives of 2-amino sugars, an inseparable mixture of diastereomers, which were derived from the corresponding C(1)-allylated glycals, has been obtained.547.78University of Bristolhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503863Electronic Thesis or Dissertation
collection	NDLTD
sources	NDLTD
topic	547.78
spellingShingle	547.78 Wang, Junwei Metal-based approaches to C(1)-substituted glycals
description	A new metal-based method to synthesize C(1)-substituted glycals has been developed. Starting with the obtained substituted C-glycals, the possibility of a stereocontrolled addition (via azidoselenation) to form β-C-substituted-2-aminoglycosides has been investigated. Instead of forming the expected C-glycosyl derivatives of 2-amino sugars, an inseparable mixture of diastereomers, which were derived from the corresponding C(1)-allylated glycals, has been obtained.
author	Wang, Junwei
author_facet	Wang, Junwei
author_sort	Wang, Junwei
title	Metal-based approaches to C(1)-substituted glycals
title_short	Metal-based approaches to C(1)-substituted glycals
title_full	Metal-based approaches to C(1)-substituted glycals
title_fullStr	Metal-based approaches to C(1)-substituted glycals
title_full_unstemmed	Metal-based approaches to C(1)-substituted glycals
title_sort	metal-based approaches to c(1)-substituted glycals
publisher	University of Bristol
publishDate	2009
url	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503863
work_keys_str_mv	AT wangjunwei metalbasedapproachestoc1substitutedglycals
_version_	1716793622052995072

Metal-based approaches to C(1)-substituted glycals

Similar Items