Effects of IGF-1, IGFBP-5 and TGFB1 on cell proliferation, attachment and migration in mammary epithelial and mesenchymal cells

Insulin-like Growth Factors (IGFs) are a determining factor in breast cancer development since high circulating concentrations of IGF-I are associated, in previous epidemiological studies, with an increased risk of breast cancer. The actions of IGF-I, which plays an important survival role for sever...

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Bibliographic Details
Main Author: Ahwaide, Hoda S.
Published: University of Strathclyde 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502317