Zaprinast as a novel therapy arterial hypertension : mechanisms of action and cannabinoids as anti-typertensives

Most pulmonary arterial hypertension therapies are centred around the use of anticoagulants, which risk haemorrhaging, and anti-hypertensive drugs, which risk systemic hypotension. The PDE5 inhibitor, zaprinast, is believed to have vasorelaxant properties specific to the pulmonary arterial bed. In t...

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Bibliographic Details
Main Author: O' Rourke, Carlyn
Published: University of Strathclyde 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502277