The development of a novel drug delivery system for the treatment of inflammatory bowel disease
The project concerns the development of a drug delivery system for the treatment of inflammatory bowel disease. This condition, which affects more than 2 million people in Europe alone, is characterised by inflammatory lesions which may be confined to the large bowel (ulcerative colitis) or extend t...
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University of Strathclyde
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501659 |
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ndltd-bl.uk-oai-ethos.bl.uk-5016592015-03-20T05:31:01ZThe development of a novel drug delivery system for the treatment of inflammatory bowel diseaseMcBride, Eileen2008The project concerns the development of a drug delivery system for the treatment of inflammatory bowel disease. This condition, which affects more than 2 million people in Europe alone, is characterised by inflammatory lesions which may be confined to the large bowel (ulcerative colitis) or extend through the intestinal tract (Crohn's disease). The components of disease activation lend themselves to treatment with immunomodulators such as the folate analogue methotrexate; although systemic sideeffects are significant. :. To o overcome this limitation, a local delivery system was investigated. In this thesis, folate has been used as a safer surrogate in the development of a silicone ribbon-based oral dosage form.616.344University of Strathclydehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501659Electronic Thesis or Dissertation |
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616.344 |
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616.344 McBride, Eileen The development of a novel drug delivery system for the treatment of inflammatory bowel disease |
| description |
The project concerns the development of a drug delivery system for the treatment of inflammatory bowel disease. This condition, which affects more than 2 million people in Europe alone, is characterised by inflammatory lesions which may be confined to the large bowel (ulcerative colitis) or extend through the intestinal tract (Crohn's disease). The components of disease activation lend themselves to treatment with immunomodulators such as the folate analogue methotrexate; although systemic sideeffects are significant. :. To o overcome this limitation, a local delivery system was investigated. In this thesis, folate has been used as a safer surrogate in the development of a silicone ribbon-based oral dosage form. |
| author |
McBride, Eileen |
| author_facet |
McBride, Eileen |
| author_sort |
McBride, Eileen |
| title |
The development of a novel drug delivery system for the treatment of inflammatory bowel disease |
| title_short |
The development of a novel drug delivery system for the treatment of inflammatory bowel disease |
| title_full |
The development of a novel drug delivery system for the treatment of inflammatory bowel disease |
| title_fullStr |
The development of a novel drug delivery system for the treatment of inflammatory bowel disease |
| title_full_unstemmed |
The development of a novel drug delivery system for the treatment of inflammatory bowel disease |
| title_sort |
development of a novel drug delivery system for the treatment of inflammatory bowel disease |
| publisher |
University of Strathclyde |
| publishDate |
2008 |
| url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501659 |
| work_keys_str_mv |
AT mcbrideeileen thedevelopmentofanoveldrugdeliverysystemforthetreatmentofinflammatoryboweldisease AT mcbrideeileen developmentofanoveldrugdeliverysystemforthetreatmentofinflammatoryboweldisease |
| _version_ |
1716791846344065024 |