Defining genes that regulate the differentiation status of neuroblastoma cell lines

Defects in differenfiafion are one of the major events presented in highly malignant leuroblastoma tumours. Evidence suggests differentiated neuroblastomas are Lssociated with improved patient outcome, but little is known regarding the molecular regulafion of differenfiation in vitro and in vivo. Al...

Full description

Bibliographic Details
Main Author:	Sung, Pei-Ju
Published:	University of Newcastle Upon Tyne 2009
Subjects:	618.929948
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500912

id	ndltd-bl.uk-oai-ethos.bl.uk-500912
record_format	oai_dc
spelling	ndltd-bl.uk-oai-ethos.bl.uk-5009122015-03-20T05:03:35ZDefining genes that regulate the differentiation status of neuroblastoma cell linesSung, Pei-Ju2009Defects in differenfiafion are one of the major events presented in highly malignant leuroblastoma tumours. Evidence suggests differentiated neuroblastomas are Lssociated with improved patient outcome, but little is known regarding the molecular regulafion of differenfiation in vitro and in vivo. Although differentiation can be induced by alternative treatments, we hypothesise that there are some genes in common that become altered and a subset of these regulate the differentiation process in neuroblastoma cells. In conclusion, a set of candidate genes were identified to be involved in the regulation of neuroblastoma cell differentiation.618.929948University of Newcastle Upon Tynehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500912Electronic Thesis or Dissertation
collection	NDLTD
sources	NDLTD
topic	618.929948
spellingShingle	618.929948 Sung, Pei-Ju Defining genes that regulate the differentiation status of neuroblastoma cell lines
description	Defects in differenfiafion are one of the major events presented in highly malignant leuroblastoma tumours. Evidence suggests differentiated neuroblastomas are Lssociated with improved patient outcome, but little is known regarding the molecular regulafion of differenfiation in vitro and in vivo. Although differentiation can be induced by alternative treatments, we hypothesise that there are some genes in common that become altered and a subset of these regulate the differentiation process in neuroblastoma cells. In conclusion, a set of candidate genes were identified to be involved in the regulation of neuroblastoma cell differentiation.
author	Sung, Pei-Ju
author_facet	Sung, Pei-Ju
author_sort	Sung, Pei-Ju
title	Defining genes that regulate the differentiation status of neuroblastoma cell lines
title_short	Defining genes that regulate the differentiation status of neuroblastoma cell lines
title_full	Defining genes that regulate the differentiation status of neuroblastoma cell lines
title_fullStr	Defining genes that regulate the differentiation status of neuroblastoma cell lines
title_full_unstemmed	Defining genes that regulate the differentiation status of neuroblastoma cell lines
title_sort	defining genes that regulate the differentiation status of neuroblastoma cell lines
publisher	University of Newcastle Upon Tyne
publishDate	2009
url	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500912
work_keys_str_mv	AT sungpeiju defininggenesthatregulatethedifferentiationstatusofneuroblastomacelllines
_version_	1716788348963520512

Defining genes that regulate the differentiation status of neuroblastoma cell lines

Similar Items