Assessing morbidity associated with standard transurethral resection of the prostate : a comparison between 1.5% glycine and 5% glucose irrigation during TURP

Despite the known complications of transurethral prostatectomy TURP remains the gold standard for benign prostatic hypertrophy causing bladder outflow obstruction. Standard TURP may predispose a patient to increased morbidity and mortality by several mechanisms including irrigating fluid absorption...

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Bibliographic Details
Main Author: Collins, J. W.
Published: University of Bristol 2007
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500219
Description
Summary:Despite the known complications of transurethral prostatectomy TURP remains the gold standard for benign prostatic hypertrophy causing bladder outflow obstruction. Standard TURP may predispose a patient to increased morbidity and mortality by several mechanisms including irrigating fluid absorption and blood loss as well as the standard risks from operating on an aged population. There is increasing evidence in the literature to support the hypotheses that glycine irrigation when absorbed is both cardiotoxic and neurotoxic. This prompted me to investigate whether two different irrigant fluids differ in terms of harmful effects and whether these differences can be measured in the perioperative period.