The fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation

The fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation

This thesis describes novel research into the generation and manipulation of aqueous droplets within a number of multiphase microfluidic platforms. Specific techniques for the mixing, dilution and sorting of droplets are reported, and the development of droplet based microreactor devices for the gen...

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Bibliographic Details
Main Author: Romeo, Mariia Pilar Carreras
Published: University of Manchester 2009
Subjects:
660.2945
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499854
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spelling ndltd-bl.uk-oai-ethos.bl.uk-4998542015-03-20T05:14:50ZThe fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentationRomeo, Mariia Pilar Carreras2009This thesis describes novel research into the generation and manipulation of aqueous droplets within a number of multiphase microfluidic platforms. Specific techniques for the mixing, dilution and sorting of droplets are reported, and the development of droplet based microreactor devices for the generation of alginate gel beads described. The alginate beads have been applied for the encapsulation of both yeast and leukemia cells, as a potential platform for the study of the behaviour of regular assemblies of cells. further modification of the platform has also demonstrated the feasibility of double layer alginate encapsulation.660.2945University of Manchesterhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499854Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 660.2945
spellingShingle 660.2945
Romeo, Mariia Pilar Carreras
The fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation
description This thesis describes novel research into the generation and manipulation of aqueous droplets within a number of multiphase microfluidic platforms. Specific techniques for the mixing, dilution and sorting of droplets are reported, and the development of droplet based microreactor devices for the generation of alginate gel beads described. The alginate beads have been applied for the encapsulation of both yeast and leukemia cells, as a potential platform for the study of the behaviour of regular assemblies of cells. further modification of the platform has also demonstrated the feasibility of double layer alginate encapsulation.
author Romeo, Mariia Pilar Carreras
author_facet Romeo, Mariia Pilar Carreras
author_sort Romeo, Mariia Pilar Carreras
title The fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation
title_short The fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation
title_full The fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation
title_fullStr The fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation
title_full_unstemmed The fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation
title_sort fabrication, integration and application of multiphase microfluidic assay platforms for high throughput experimentation
publisher University of Manchester
publishDate 2009
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499854
work_keys_str_mv AT romeomariiapilarcarreras thefabricationintegrationandapplicationofmultiphasemicrofluidicassayplatformsforhighthroughputexperimentation
AT romeomariiapilarcarreras fabricationintegrationandapplicationofmultiphasemicrofluidicassayplatformsforhighthroughputexperimentation
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