Synthesis of telomerase inhibitors based on polyoxazoles
This thesis focuses on the synthesis of compounds expected to inhibit telomerase and provide potential for the treatment of cancer. Telomerase is a reverse transcriptase enzyme, which codes for telomeres and define the ends of chromosomes. Abnormal telomerase activity occurs in 85% of cancer cells a...
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University College London (University of London)
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498507 |