Synthetic studies towards the total synthesis of the neocarzinostatin chromophore

The chromoprotein Neocarzinostatin (NCS) was the first isolated member of the so- called 'enediyne' class of antibiotics and was found to exhibit broad-spectrum antitumor activity. NCS was isolated in 1965 from the bacterium Streptomyces carzinostaticus and is made up of a 1:1 non-covalent...

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Bibliographic Details
Main Author: Thominet, Olivier Gaston Andre
Published: University College London (University of London) 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497616