Synthetic studies towards the total synthesis of the neocarzinostatin chromophore
The chromoprotein Neocarzinostatin (NCS) was the first isolated member of the so- called 'enediyne' class of antibiotics and was found to exhibit broad-spectrum antitumor activity. NCS was isolated in 1965 from the bacterium Streptomyces carzinostaticus and is made up of a 1:1 non-covalent...
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University College London (University of London)
2007
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497616 |