Approaches towards the total synthesis of the 20-deoxy bryostatins

This thesis describes approaches towards the total synthesis of the 20-deoxy bryostatins. The use of CI9 acyl anion equivalents as a means of forming the C19-C20 bond was investigated, leading to the synthesis of 2-[(2'E,6'Z)-(R)-6'-(2-benzyloxymethoxy-ethyl)-1', 1' -dimethy...

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Bibliographic Details
Main Author: Hardy, Simon
Published: University of Manchester 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496225