Molecular interactions of pyrethroid insecticides with insect ion channels
Much of the present knowledge of the activity of pyrethroids on the insect Na⁺ channel has come from the electrophysiological investigation of Na⁺ channels expressed heterologously in the Xenopus laevis oocyte expression system. The effects of the naturally occurring pyrethroid resistance mutations,...
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ndltd-bl.uk-oai-ethos.bl.uk-4955292015-03-20T04:57:29ZMolecular interactions of pyrethroid insecticides with insect ion channelsVerdin, Paul Stephen2008Much of the present knowledge of the activity of pyrethroids on the insect Na⁺ channel has come from the electrophysiological investigation of Na⁺ channels expressed heterologously in the Xenopus laevis oocyte expression system. The effects of the naturally occurring pyrethroid resistance mutations, located within the Na⁺ channel gene(s), have also been studied in this way. These studies have yielded a wealth of information, but make several assumptions - that insect Na⁺ channels behave normally in this alien environment and that the expressed channels accurately represent the range channels present in neurons.632.9517University of Nottinghamhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495529Electronic Thesis or Dissertation |
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632.9517 Verdin, Paul Stephen Molecular interactions of pyrethroid insecticides with insect ion channels |
description |
Much of the present knowledge of the activity of pyrethroids on the insect Na⁺ channel has come from the electrophysiological investigation of Na⁺ channels expressed heterologously in the Xenopus laevis oocyte expression system. The effects of the naturally occurring pyrethroid resistance mutations, located within the Na⁺ channel gene(s), have also been studied in this way. These studies have yielded a wealth of information, but make several assumptions - that insect Na⁺ channels behave normally in this alien environment and that the expressed channels accurately represent the range channels present in neurons. |
author |
Verdin, Paul Stephen |
author_facet |
Verdin, Paul Stephen |
author_sort |
Verdin, Paul Stephen |
title |
Molecular interactions of pyrethroid insecticides with insect ion channels |
title_short |
Molecular interactions of pyrethroid insecticides with insect ion channels |
title_full |
Molecular interactions of pyrethroid insecticides with insect ion channels |
title_fullStr |
Molecular interactions of pyrethroid insecticides with insect ion channels |
title_full_unstemmed |
Molecular interactions of pyrethroid insecticides with insect ion channels |
title_sort |
molecular interactions of pyrethroid insecticides with insect ion channels |
publisher |
University of Nottingham |
publishDate |
2008 |
url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495529 |
work_keys_str_mv |
AT verdinpaulstephen molecularinteractionsofpyrethroidinsecticideswithinsectionchannels |
_version_ |
1716787644646555648 |