Priming of STAT1 and STAT3 for cytokine-triggered degradation by the proteasome upon A2Aadenosine receptor (A2AAR) expression
The A2A adenosine receptor (A2AAR) functions as a key non-redundant suppressor of inflammatory responses in vivo. However, whether it regulates activation of the JAK-STAT pathway utilised by many pro-inflammatory cytokines is unknown. Using a vascular endothelial cell model system, I have demonstrat...
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University of Glasgow
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495313 |