Target site selection of retroviral vectors in the human genome : viral and genomic determinants of non-random integration patterns in hematopoietic cells

Integration of gamma-retroviruses (RV) and lehtiviruses (LV) follows different, non random patterns in mammalian genomes. To obtain information about the viral and genomic determinants of integration preferences, I mapped > 2,500 integration sites of RV and LV vectors carrying wild type or modifi...

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Bibliographic Details
Main Author: Cattoglio, Claudia
Published: Open University 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494505