Modelling pharmacokinetics in heterogeneous populations : impact of pharmacogenetics and age

The goal of most population pharmacokinetic and pharmacodynamic analyses is to develop a model that adequately describes the available data and that can be used for predictive purposes. The assessment of covariates is of utmost importance to enhance predictive performance and ultimately to design ra...

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Bibliographic Details
Main Author: Matthews, Ivan Thomas
Published: University of Manchester 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493911