Evaluation of Bcl-2 Family Targeting Therapeutics in neuroblastoma

Evaluation of Bcl-2 Family Targeting Therapeutics in neuroblastoma

Neuroblastoma is the commonest extracranial solid tumour of childhood and often has a poor outcome. Resistance to chemotherapy is a common problem and despite advances in treatment over recent years new strategies are needed. The aim of this project was an investigation of hypoxia mediated drug resi...

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Main Author: Brandenburg, Martin
Published: University of Manchester 2008
Subjects:
618.929948
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493457
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spelling ndltd-bl.uk-oai-ethos.bl.uk-4934572015-03-20T05:14:09ZEvaluation of Bcl-2 Family Targeting Therapeutics in neuroblastomaBrandenburg, Martin2008Neuroblastoma is the commonest extracranial solid tumour of childhood and often has a poor outcome. Resistance to chemotherapy is a common problem and despite advances in treatment over recent years new strategies are needed. The aim of this project was an investigation of hypoxia mediated drug resistance in neuroblastoma and the characterisation of the novel apoptosis based therapeutic ABT-737.618.929948University of Manchesterhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493457Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 618.929948
spellingShingle 618.929948
Brandenburg, Martin
Evaluation of Bcl-2 Family Targeting Therapeutics in neuroblastoma
description Neuroblastoma is the commonest extracranial solid tumour of childhood and often has a poor outcome. Resistance to chemotherapy is a common problem and despite advances in treatment over recent years new strategies are needed. The aim of this project was an investigation of hypoxia mediated drug resistance in neuroblastoma and the characterisation of the novel apoptosis based therapeutic ABT-737.
author Brandenburg, Martin
author_facet Brandenburg, Martin
author_sort Brandenburg, Martin
title Evaluation of Bcl-2 Family Targeting Therapeutics in neuroblastoma
title_short Evaluation of Bcl-2 Family Targeting Therapeutics in neuroblastoma
title_full Evaluation of Bcl-2 Family Targeting Therapeutics in neuroblastoma
title_fullStr Evaluation of Bcl-2 Family Targeting Therapeutics in neuroblastoma
title_full_unstemmed Evaluation of Bcl-2 Family Targeting Therapeutics in neuroblastoma
title_sort evaluation of bcl-2 family targeting therapeutics in neuroblastoma
publisher University of Manchester
publishDate 2008
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493457
work_keys_str_mv AT brandenburgmartin evaluationofbcl2familytargetingtherapeuticsinneuroblastoma
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