Expression, purification characterisation of the extracellular N-terminal domain of human neuronal a nicotinic acetylcholine receptor of E coli and insect cells

This thesis was aimed at the over-expression of the extracellular N-terminal domain (ECD) of the human a7 nicotinic acetylcholine receptor (nAChR). The ECD of the a7 nAChR is more suitable than the ECD of other nAChR subunits for crystallographic studies, mainly because the receptor is oligomeric an...

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Bibliographic Details
Main Author: Ferrandon, Sebastien
Published: Oxford Brookes University 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493414