Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha

Metallothioneins (MT) are small metal-binding proteins. Metallothionein isoform MT-1 alters localization from cytoplasm to nucleus as cells enter S phase. The perinuclear localization of MT-1 mRNA is essential for this nuclear localization. The localization of the MT-1 mRNA requires a signal in the...

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Main Author: Fan, Kunbo
Published: University of Newcastle Upon Tyne 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493226
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spelling ndltd-bl.uk-oai-ethos.bl.uk-4932262015-03-20T05:03:35ZStudy of metallothionein-1 mRNA and its interaction with elongation factor 1 alphaFan, Kunbo2008Metallothioneins (MT) are small metal-binding proteins. Metallothionein isoform MT-1 alters localization from cytoplasm to nucleus as cells enter S phase. The perinuclear localization of MT-1 mRNA is essential for this nuclear localization. The localization of the MT-1 mRNA requires a signal in the 3'untranslated region (3'UTR). This thesis describes studies of the localization signal in the MT-1 3'UTR and its binding to transacting cellular proteins.572.68Bioactive proteinsUniversity of Newcastle Upon Tynehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493226Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 572.68
Bioactive proteins
spellingShingle 572.68
Bioactive proteins
Fan, Kunbo
Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha
description Metallothioneins (MT) are small metal-binding proteins. Metallothionein isoform MT-1 alters localization from cytoplasm to nucleus as cells enter S phase. The perinuclear localization of MT-1 mRNA is essential for this nuclear localization. The localization of the MT-1 mRNA requires a signal in the 3'untranslated region (3'UTR). This thesis describes studies of the localization signal in the MT-1 3'UTR and its binding to transacting cellular proteins.
author Fan, Kunbo
author_facet Fan, Kunbo
author_sort Fan, Kunbo
title Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha
title_short Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha
title_full Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha
title_fullStr Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha
title_full_unstemmed Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha
title_sort study of metallothionein-1 mrna and its interaction with elongation factor 1 alpha
publisher University of Newcastle Upon Tyne
publishDate 2008
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493226
work_keys_str_mv AT fankunbo studyofmetallothionein1mrnaanditsinteractionwithelongationfactor1alpha
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