Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha
Metallothioneins (MT) are small metal-binding proteins. Metallothionein isoform MT-1 alters localization from cytoplasm to nucleus as cells enter S phase. The perinuclear localization of MT-1 mRNA is essential for this nuclear localization. The localization of the MT-1 mRNA requires a signal in the...
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ndltd-bl.uk-oai-ethos.bl.uk-4932262015-03-20T05:03:35ZStudy of metallothionein-1 mRNA and its interaction with elongation factor 1 alphaFan, Kunbo2008Metallothioneins (MT) are small metal-binding proteins. Metallothionein isoform MT-1 alters localization from cytoplasm to nucleus as cells enter S phase. The perinuclear localization of MT-1 mRNA is essential for this nuclear localization. The localization of the MT-1 mRNA requires a signal in the 3'untranslated region (3'UTR). This thesis describes studies of the localization signal in the MT-1 3'UTR and its binding to transacting cellular proteins.572.68Bioactive proteinsUniversity of Newcastle Upon Tynehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493226Electronic Thesis or Dissertation |
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572.68 Bioactive proteins |
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572.68 Bioactive proteins Fan, Kunbo Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha |
description |
Metallothioneins (MT) are small metal-binding proteins. Metallothionein isoform MT-1 alters localization from cytoplasm to nucleus as cells enter S phase. The perinuclear localization of MT-1 mRNA is essential for this nuclear localization. The localization of the MT-1 mRNA requires a signal in the 3'untranslated region (3'UTR). This thesis describes studies of the localization signal in the MT-1 3'UTR and its binding to transacting cellular proteins. |
author |
Fan, Kunbo |
author_facet |
Fan, Kunbo |
author_sort |
Fan, Kunbo |
title |
Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha |
title_short |
Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha |
title_full |
Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha |
title_fullStr |
Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha |
title_full_unstemmed |
Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha |
title_sort |
study of metallothionein-1 mrna and its interaction with elongation factor 1 alpha |
publisher |
University of Newcastle Upon Tyne |
publishDate |
2008 |
url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493226 |
work_keys_str_mv |
AT fankunbo studyofmetallothionein1mrnaanditsinteractionwithelongationfactor1alpha |
_version_ |
1716788300117704704 |