Inter-Individual Variation in CYP3A4 and CYP3A5- Mediated Drug Metabolism
Cytochrome P450 enzymes, especially those of the CYP3A family, play a major role in the metabolism of many drugs.' Patient response to drugs metabolized by CYP3A4 and CYP3A5 varies considerably and part of this variability is due to genetic polymorphism ot the CYP3A5 enzyme. In this study, huma...
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University of Manchester
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492887 |