Characterisation of the atypical calpain family of C elegans
Regulated proteolysis plays an important role in modulating the activities of receptors, cytoskeletal proteins and transcription factors during cell growth and development. A family of calcium-regulated thiol proteases, known as calpains, has been shown to promote this process in mammals, and other...
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University of Bristol
2008
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492634 |
| Summary: | Regulated proteolysis plays an important role in modulating the activities of receptors, cytoskeletal proteins and transcription factors during cell growth and development. A family of calcium-regulated thiol proteases, known as calpains, has been shown to promote this process in mammals, and other eukaryotes. The importance of calpains is highlighted through their involvement in a number of pathologies in humans. |
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