The impact of Toll-like receptors on antigen presentation by mouse macrophages

Toll-like receptors (TLRs) are a group of trans-membrane proteins playing important roles as pattern-recognition receptors (PRRs) of innate immunity that are mainly expressed on professional antigen presenting cells (APCs). Stimulation of APC with TLR ligands, a variety of Jnolecular components deri...

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Main Author: Pupjain, Srijan
Published: University of Newcastle Upon Tyne 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491833
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spelling ndltd-bl.uk-oai-ethos.bl.uk-4918332015-03-20T05:03:36ZThe impact of Toll-like receptors on antigen presentation by mouse macrophagesPupjain, Srijan2008Toll-like receptors (TLRs) are a group of trans-membrane proteins playing important roles as pattern-recognition receptors (PRRs) of innate immunity that are mainly expressed on professional antigen presenting cells (APCs). Stimulation of APC with TLR ligands, a variety of Jnolecular components derived from microorganisms, triggers innate immunity and establishes adaptive immune responses. I studied the impact of TLR specific for bacterial components on antigen processing and presentation of protective antigen (PA) of B. anthracis by bone marrow macrophages from mice.571.96University of Newcastle Upon Tynehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491833Electronic Thesis or Dissertation
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topic 571.96
spellingShingle 571.96
Pupjain, Srijan
The impact of Toll-like receptors on antigen presentation by mouse macrophages
description Toll-like receptors (TLRs) are a group of trans-membrane proteins playing important roles as pattern-recognition receptors (PRRs) of innate immunity that are mainly expressed on professional antigen presenting cells (APCs). Stimulation of APC with TLR ligands, a variety of Jnolecular components derived from microorganisms, triggers innate immunity and establishes adaptive immune responses. I studied the impact of TLR specific for bacterial components on antigen processing and presentation of protective antigen (PA) of B. anthracis by bone marrow macrophages from mice.
author Pupjain, Srijan
author_facet Pupjain, Srijan
author_sort Pupjain, Srijan
title The impact of Toll-like receptors on antigen presentation by mouse macrophages
title_short The impact of Toll-like receptors on antigen presentation by mouse macrophages
title_full The impact of Toll-like receptors on antigen presentation by mouse macrophages
title_fullStr The impact of Toll-like receptors on antigen presentation by mouse macrophages
title_full_unstemmed The impact of Toll-like receptors on antigen presentation by mouse macrophages
title_sort impact of toll-like receptors on antigen presentation by mouse macrophages
publisher University of Newcastle Upon Tyne
publishDate 2008
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491833
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