Characterization of NSl glycosylation mutant viruses as a potential vaccine candidate for West Nile virus

West Nile virus (\VNV) is a mosquito-borne flavivirus that has N-linked glycosylation sites on the premembrane (prM) envelope (E) and nonstructural 1 (NS1) proteins. NS1 contains three glycosylation (asparagine-X-threoine [NXT]) sites at NS1130, NS1175, and NSh07. The fIrst aim ofthe thesis was to a...

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Bibliographic Details
Main Author: Whiteman, Melissa Christine
Published: University of Liverpool 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490657