Mechanisms of cardiac pleiotrophy in cited 2 dificiency
How can a single gene defect present with a varied phenotype- Cited2 gene deletion in the mouse results in pleiotropic, penetrant and variable cardiovascula malformations, laterality defects, adrenal agenesis, neural tube defects and fused cranial ganglia. CITED2 acts as a transcriptional co-activat...
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University of Oxford
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490109 |