S1P,LPA and TRK a receptor expression, activation and signal transduction in various cell types

Lysophosphatidate (LPA) binds to a family of G-protein coupled receptors (GPCR). Three receptors belong to the endothelial differentiation gene (EDG) family, namely LPA1-3. whereas another two receptors LPA4-5 are evolutionary distant. The LPA1receptor couples to effectors via the heterotrimeric G-p...

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Bibliographic Details
Main Author: Moughal, Noreen Akhtar
Published: University of Strathclyde 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487875