Genetic aspects of autoimmune diabetes with particular reference to the role of HLA

The HLA-DQ molecule is an important determinant of the risk of type 1 diabetes. The level of expression of predisposing and protective DQ variants may contribute to their influence on disease risk. Chapter 2 shows that the alleles encoding these variants differ in their expression at the mRNA level;...

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Bibliographic Details
Main Author: Britten, Abigail Caroline
Published: University of Birmingham 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487514