DUB3/USP17 regulates cell growth and movement, and ras-like GTPase processing and activation

The deubiquitinating enzyme DUB3IUSPl7 CUSPI 7) is a cytokine inducible gene that blocks cell proliferation. In this study we have shown that the RasIERKI/2 MAP Kinase pathway and cell proliferation were perturbed in the presence ofUSPI7. Specifically, we have found that USPl7 targets the Ras conver...

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Bibliographic Details
Main Author: Kelvin, Alyson Ann
Published: Queen's University Belfast 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486228

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