The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction

The macrophage colony stimulating factor receptor encoded by the csf1r (formally known as c-fms) gene is a tyrosine kinase receptor which is essential for macrophage differentiation. This gene is upregulated during macrophage differentiation, but silenced in all non-macrophage cells. Previous studie...

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Bibliographic Details
Main Author: Wilson, Nicola Kaye
Published: University of Leeds 2007
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485916