Design, synthesis and SAR studies of pyridine dicarbonitriles as potential prion therapeutics
Transmissible spongiform encephalopathies (TSEs) also known as prion diseases are a family of invariably fatal neurodegenerative disorders which affect a range of mammalian species. As yet no effective therapy exists for the prevention of either infection or disease progression. It is clear that eff...
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University of Sheffield
2006
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485118 |