Dihydro-Imidazo Phenanthridinium (DIP)-based DNA Binding Agents with Tuneable Structures and Biological Activity

A new class ofphenanthridinium derivative (DIP) has been isolated from the reaction of 2-bromoethyl-phenanthridinium bromide with a range of primary amines in excellent yields. The reaction has been used to create a large library of compounds which have been tested for DNA affinity by Isothermal Tit...

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Bibliographic Details
Main Author: Smith, Louise Victoria
Published: University of Glasgow 2006
Subjects:
615
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.484912