Investigating the role of specific LEF/TCF transcription factors in colorectal cancer

We have shown that LEF-1 protein is expressed in both HCT116 and SW480 colorectal cancer cell lines, consistent with its expression in colorectal cancer tissue, and, using PCR, have examined the expression of specific Tcf-1, Lef-1, Tcf-3 and Tcf-4 isoforms in these cells. this analysis showed that r...

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Bibliographic Details
Main Author: Kavanagh, Claire Louise
Published: University of Aberdeen 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446607