Investigation of a role for noradrenaline in the neurochemical and behavioural effects of an established and putative target for antianxiety/antidepressant drugs : a microdialysis and behavioural study in rats and NK1 receptor knockout mice

The precise neurochemical effects of antidepressants that underlie their efficacy remain unclear. Many antidepressants modulate noradrenaline transmission in vivo. However, the selective serotonin reuptake inhibitors (SSRIs) and NK1 receptor antagonists target 5-HT and substance P transmission, resp...

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Bibliographic Details
Main Author: Stewart, Robert John
Published: University College London (University of London) 2005
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433005