The role of EBV latent membrane protein 1 induced regulatory T-cells in latent infection and Hodgkin lymphoma

Healthy EBV seropositive donors tested for the ability to mount Th responses against LMP1 responded with secretion of high levels of the immunosuppressive cytokine IL-10 which was secreted from cells phenotypically analogous to the Tr1 class of regulatory T-cells.  The epitopes inducing this IL-10 s...

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Bibliographic Details
Main Author: Marshall, Neil A.
Published: University of Aberdeen 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430397