A study of a mutant form of receptor tyrosine kinase Tie-2 associated with venous malformations
The receptor tyrosine kinase Tie-2 is expressed predominantly in endothelial cells and is involved in blood vessel formation and maintenance. A missense mutation resulting in an R849 to W substitution in the kinase domain of Tie-2 has been reported to co-segregate with an autosomal dominantly inheri...
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University of Leicester
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426041 |