Binding of the hepatitis C virus E2 glycoprotein to CD81 and other receptors on immune system cells, and immunomodulatory functions of CD81 on innate cell subsets
Hepatitis C virus (HCV) persists in ~80% of infected individuals. The mechanisms involved in HCV persistence and pathogenesis are not fully understood. The E2 envelope glycoprotein of HCV has been shown to bind to CD81, and it is hypothesised that E2 cross-linking of CD81 may have immunomodulatory e...
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University College London (University of London)
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424301 |