Studies on the cellular function of the uPA/uPAR system

The uPA receptor, uPAR, is GPI-linked and therefore contains no transmembrane domains.  Yet, uPA:uPAR binding can initiate cell signalling and may involve adaptor proteins, such as integrins.  Various responses to uPA binding have been described, but the exact mechanisms remain undefined. To identif...

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Bibliographic Details
Main Author: Barson, Helen
Published: University of Aberdeen 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419648