Drug uptake, sensitivity, interaction studies and resistance associated mutations in Plasmodium falciparum
Evidence is accumulating that polymorphisms in plmdr 1 and plcrt are involved in resistance to the quinoline based blood schizontocides and possibly artemisinin derivatives; and mutations in the cytochrome b gene (cytb) are strongly associated with resistance to atovaquone. With this in mind, we stu...
Main Author: | Fivelman, Quinton Leonard |
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Other Authors: | Warhurst, David C. ; Adagu, Ipemida Sullayman |
Published: |
London School of Hygiene and Tropical Medicine (University of London)
2003
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Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406121 |
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