Drug uptake, sensitivity, interaction studies and resistance associated mutations in Plasmodium falciparum

Evidence is accumulating that polymorphisms in plmdr 1 and plcrt are involved in resistance to the quinoline based blood schizontocides and possibly artemisinin derivatives; and mutations in the cytochrome b gene (cytb) are strongly associated with resistance to atovaquone. With this in mind, we stu...

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Bibliographic Details
Main Author: Fivelman, Quinton Leonard
Other Authors: Warhurst, David C. ; Adagu, Ipemida Sullayman
Published: London School of Hygiene and Tropical Medicine (University of London) 2003
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406121