The design of a prodrug to utilise the thymidine phosphorylase enzyme

The current study has investigated the design of a prodrug to utilise the thymidine phosphorylase enzyme, based on combining HPMA copolymer technology with a thymidine analogue to deliver 5-fluorouracil or other cytotoxic agents selectivity to cancer tumours.  A detailed review has been compiled cov...

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Bibliographic Details
Main Author: Campbell, Robert Malcolm
Published: University of Aberdeen 2003
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400668