Physiological and pathological role of inhibitors of fibrinolysis
The activity of the fibrinolytic system is dependent on the activation of plasminogen to plasmin by the activators t-PA and u-PA. These proteases are regulated by plasminogen activator inhibitor 1 (PAI-1); 2-antiplasmin (2-AP) inhibits the plasmin generated by their action. Both PAI-1 and 2-AP occur...
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University of Aberdeen
1994
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385974 |