Conformation and activity of plasminogen activator inhibitor type 1 (PAI-1)

Plasminogen activator inhibitor type 1 (PAI-1) is a unique member of the serpins in that it can adopt various conformations. It is synthesized as an active inhibitor which rapidly converts to a latent form that is not inhibitory. Conformational studies on this protein have been made difficult by thi...

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Bibliographic Details
Main Author: Sancho, Elena
Published: University of Aberdeen 1994
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385547